
1512 E Griffin Pky Ste 2 Mission, TX. 78572
Ph:
956-519-7088
Fax:
956-519-9816
OUR PRACTICE
For more than three decades, Dr. Mario R. Anzaldua has dedicated his career to caring for individuals and families throughout the Rio Grande Valley. Since making Mission, Texas his home in 1988, he has built his practice around a simple philosophy: provide compassionate, personalized healthcare while treating every patient with dignity, respect, and genuine care.
What began as a small medical office with a close-knit team has grown alongside the community into a thriving family practice serving generations of patients. Over the years, continued growth and the trust of local families led to the expansion into a larger, modern facility designed to provide greater comfort, convenience, and access to care.
Despite the growth, the heart of the practice has remained the same. Dr. Anzaldua and his team strive to create a welcoming environment where patients are known, heard, and cared for-not simply treated. From longtime patients who have been with the practice for years to families visiting for the first time, the goal is to make every person who walks through the doors feel at home.
Today, Dr. Anzaldua's Family Practice continues to proudly serve Mission and communities throughout the Rio Grande Valley, carrying forward a tradition of trusted, patient-centered care built over more than 30 years.

Mario R. Anzaldua, MD
Dr. Anzaldua earned his Bachelor’s Degree in Human Biology from Stanford University before obtaining his Medical Doctor degree from The University of Texas Health Science Center at San Antonio. His educational background, combined with decades of clinical experience, has shaped his philosophy of providing compassionate, accessible, and patient-centered medical care.
Throughout his career, Dr. Anzaldua has remained committed to improving the health and well-being of individuals and families throughout the Rio Grande Valley. His vision has always extended beyond simply treating an illness. He believes a medical practice should be a place where patients feel heard, respected, and genuinely cared for, while receiving the medical attention and guidance necessary to meet their individual healthcare needs.
At the heart of Dr. Anzaldua's vision is a commitment to building lasting relationships with patients and their families. He believes strongly in preventive medicine, early intervention, continuity of care, and helping patients understand and actively participate in their healthcare. His goal is to create a practice where quality medical care and exceptional patient service work together-not as separate priorities, but as equally important parts of the patient experience.
That philosophy guides the standards he establishes for his entire practice. Dr. Anzaldua expects every member of his team-from providers and clinical staff to administrative personnel-to recognize that each patient deserves compassion, professionalism, respect, and timely attention to their medical needs. His vision is for patients to know that they have a healthcare team that will advocate for them, coordinate their care, and remain accessible when they need assistance.
For Dr. Anzaldua, caring for the community also means continually adapting the practice to meet the changing healthcare needs of its patients. His focus remains on providing comprehensive primary care, promoting wellness and prevention, managing chronic medical conditions, and coordinating specialty and hospital care when needed.
To further support continuity and coordination of care, Dr. Anzaldua maintains affiliations with several healthcare institutions in the Rio Grande Valley, including Mission Regional Medical Center, Doctors Hospital at Renaissance, and South Texas Health System.
After decades of serving the community, Dr. Anzaldua's mission remains centered on a simple principle: patients deserve to be treated as persons. His vision continues to guide the practice today-to provide quality medical care while creating an environment where patients and their families know they are valued, supported, and cared for throughout every stage of their healthcare journey.

Karina S Cantu, FNP-BC
Ms. Cantu earned her Bachelor of Science in Nursing from The University of Texas Rio Grande Valley and began her healthcare career serving patients as both an Emergency Room and Operating Room Registered Nurse. Her passion for patient care and commitment to advancing her medical knowledge led her to pursue and obtain her Master of Science in Nursing from the same institution.
With years of hands-on clinical experience, Ms. Cantu is dedicated to helping patients achieve healthier and more fulfilling lives through compassionate, personalized care. She believes in treating every patient with kindness, respect, and understanding while encouraging them to take an active role in improving their overall well-being. By building strong relationships with her patients, she creates a welcoming environment where individuals feel comfortable, valued, and supported throughout their healthcare journey.
Outside of the office, Ms. Cantu is deeply family-oriented and enjoys spending quality time with her loved ones. She also has a passion for traveling and experiencing new places and cultures. Guided by strong faith and values, she approaches both her personal life and patient care with compassion, integrity, and dedication.

Rolando Benitez, MPAS, PA-C
Rolando Benitez is a nationally certified Physician Assistant through the National Commission on Certification of Physician Assistants and licensed by the Texas State Medical Board of Physician Assistants. With more than three decades of experience, he specializes in family medicine and the care of work-related injuries.
Mr. Benitez earned his Bachelor of Science in Physician Assistant Studies from the University of Texas Medical Branch, School of Allied Health Sciences in Galveston in 1991, and later completed his Master of Physician Assistant Studies at the University of Texas-Pan American in 2011.
Throughout his career, he has developed advanced expertise in family practice, with a particular focus on diabetes management, workers' compensation care, and preventive medicine. He is also a Certified Medical Examiner for the National Registry of Certified Medical Examiners (NRCME), authorized to perform Department of Transportation physicals for commercial drivers.
Having practiced in the community where he was raised, Mr. Benitez takes pride in providing continuity of care across generations. Caring for the children and grandchildren of longtime patients is a testament to the trust and long-lasting relationships that define his approach to medicine.

Nilda Olmeda, FNP-BC
Ms. Olmeda earned both her Bachelor of Science in Nursing and Master of Science in Nursing with a Family Nurse Practitioner concentration from the University of Texas-Pan American. Prior to obtaining her master's degree, she worked as a registered nurse in a hospital telemetry setting, where she gained extensive experience caring for patients with acute and chronic medical conditions. This strong clinical foundation continues to influence her comprehensive and patient-centered approach to care.
With more than 14 years of experience in family practice, Ms. Olmeda provides comprehensive primary care to patients across the lifespan, with a focus on prevention, wellness, and the management of acute and chronic health conditions. Guided by her Christian faith and a commitment to serving others, Ms. Olmeda strives to treat each patient with compassion, dignity, and respect. She values building lasting relationships with her patients and empowering them to make informed decisions that support their health and well-being.

Randolph Valenzuela, DNP, APRN, ACNP-BC
Dr. Valenzuela is a board-certified Acute Care Nurse Practitioner specializing in Adult-Gerontology care. With more than 21 years of nursing experience spanning critical care, emergency medicine, and executive nursing leadership, Dr. Valenzuela brings a comprehensive and patient focused approach to healthcare.
Dr. Valenzuela holds a dual Doctor of Nursing Practice (DNP) and Doctor of Philosophy (PhD) from Texas Christian University, as well as a Master of Business Administration (MBA) from Michigan State University. His diverse educational background combines advanced clinical expertise, research acumen, and healthcare leadership, allowing him to deliver evidence-based, high-quality care while fostering innovation.
At the core of Dr. Valenzuela's practice are four guiding pillars: patient-centered care, shared decision-making, quality of care, and preventive medicine. He believes that successful healthcare outcomes are achieved through strong partnership between patients and providers, empowering individuals to take an active role in their health and wellness.
Originally from California, Dr. Valenzuela has proudly served the Mission, Texas community for more than five years. He is dedicated to improving the health and well-being of the populations he serves through compassionate care. Outside of his professional responsibilities, Dr. Valenzuela is an avid fitness enthusiast who believes that a strong mind and body are inseparable. He enjoys spending time at South Padre Island, exploring the open road on his motorcycle, and pursuing his fascination with astrophysics and the mysteries of the space-time continuum.

Leticia Cobos, PA-C
Ms. Cobos is a highly experience and dedicated Physician Assistant, certified by the National Commission on Certification of Physician Assistants and licensed through the Texas Medical Board. She earned her Master of Physician Studies degree from The University of Texas-Pan American in 2012 and has since devoted her career to providing exceptional healthcare to patients throughout the Rio Grande Valley.
With more than 13 years of experience in Internal Medicine and 12 years of experience in Pediatrics, Ms. Cobos brings a well-rounded approach to patient care, allowing her to effectively treat individuals across multiple stages of life. Her extensive clinical background has equipped her with the knowledge and expertise to diagnose, treat, and manage a wide range of acute and chronic medical conditions.
Ms. Cobos is passionate about helping patients achieve and maintain their best possible health through education, prevention, and personalized treatment plans. She places a strong emphasis on preventive care and early intervention, believing that proactive healthcare is one of the most effective ways to improve long-term outcomes and quality of life. Her compassionate approach, attention to detail, and commitment to patient wellness have earned her the trust and appreciation of the patients and families she serves.
Dedicated to building meaningful relationships with her patients, Ms. Cobos strives to create a supportive and welcoming environment where individuals feel comfortable discussing their healthcare needs and actively participating in their journey toward better health.

Lee Haak, MD
Dr. Haak earned his Bachelor's degree in Biology from the University of Houston before graduating from Texas A&M College of Medicine. Dr. Haak grew up in Harlingen, and he maintains deep roots in this community.
He completed the McLennan County Residency Program in Waco, Tx. and has been Board Certified in Family Medicine since 2003. Dr. Haak started his career working in a primary care clinic and has also worked in ER medicine and Urgent Care.
For the last eight years, Dr. Haak has been serving Hidalgo County as a Hospitalist for Dr. Nunez group. Through the years of advocating for his hospital patients, Dr. Haak has developed strong relationships with the specialists in our community such as Nephrology, Cardiology and Wound Care.
We think Dr. Haak will help Dr. Anzaldua's clinic continue to grow and better serve our patients. We are excited to welcome him to our team.

The Team
Behind every great practice is a dedicated team committed to making each patient feel welcomed, cared for, and supported. Dr. Mario R. Anzaldua and his staff work together to provide compassionate, dependable care-from the moment patients walk through the door to scheduling, clinical support, follow-up, and everything in between. Our team takes pride in creating a friendly, professional environment where patients and their families are treated with kindness, respect, and personalized attention.

Clinic Administrator
Nancy B. Cortez serves as Clinic Administrator for Mario R. Anzaldua, MD PA, where she has had the privilege of working closely alongside Dr. Anzaldua for 26 years. Nancy completed General Studies at South Texas College (STC), has completed additional technical trainings, and holds certifications in Medical Billing and Health and Medical Administrative Services. Her education, specialized training and decades of hands-on experience have provided her with a strong foundation in healthcare administration and medical practice operations.
Through her many years working alongside Dr. Anzaldua, Nancy has developed a deep understanding of his vision, his standards for the practice, and his commitment to providing compassionate, quality care to every patient.
As Clinic Administrator, Nancy is dedicated to carrying out that vision by helping ensure patients receive not only the medical care they need, but also the compassion, respect, communication, and customer service they deserve.
Patient advocacy is at the heart of Nancy's role. She works closely with patients, providers, staff, insurance plans, and other healthcare organizations to help address concerns, overcome barriers to care, and ensure patients feel heard and supported.
For Nancy, being Clinic Administrator is more than managing the daily operations of the practice-it is about supporting Dr. Anzaldua's vision and advocating for the patients who have entrusted the practice with their care.
If you encounter an issue with our practice or feel that your needs have not been properly addressed, Nancy encourages you to contact her directly. Your concerns and your experience matter.
Nancy B. Cortez | Clinic Administrator
956-519-7088, Ext. 250

Assistant Clinic Administrator
Alejandra Rios has been a valued member of the clinic team for three years and serves as Assistant Clinic Administrator, with a primary focus on Human Resources and administrative operations. In her role, she works closely with Clinic Administrator Nancy Cortez to support the team, strengthen day to day operations, and help foster a positive and professional environment for both staff and patients.
Alejandra holds a Bachelor of Science in Rehabilitative Services from The University of Texas Rio Grande Valley. Her background has strengthened her passion for serving others and has shaped her compassionate, people-centered approach to healthcare.
Committed to making every patient feel heard, respected, and cared for, Alejandra strives to support a culture centered on compassionate service, preventive care, patient advocacy, and giving back to the Rio Grande Valley community.
Alejandra Rios | Assistant Clinic Administrator